Wednesday, October 21, 2009

explain the role of Vit. K in blood clot formation?


Answer:
above answer is pretty good, but vitamin K is involved in reactions that make those compounds active. without K, they're still made, just not usable.
part of the blood's clotting abilities a depoendent on vit k. for those who take the medication cumiden, a blood thinner, if they get too much cumiden in their system they can litterally bleed to death through the kidneys. vit. k is used to counteract the thinning of the blood and facilitate clotting.
The clotting cascade is basically a series of enzymatic conversions that lead to activation of fibrin, which is the main functional component of a clot. Vitamin K is necessary for the synthesis several of the intermediate enzymes involved -- namely Factor II, VII, IX, and X. Vitamin K deficiency then does not allow these enzymes to be produced, and subsequently participate in the proper formation of a clot.

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