Wednesday, October 21, 2009

Explain the role of iron,folic acid and Vit. B12 in production of RBC?


Answer:
Iron plays a key role in the production of haemoglobin within our red blood cells (RBC), where it is required for oxygen transportation from the lungs to the body's tissues and the carbon dioxide transportation from the tissues to the lungs. Iron is also required for the synthesis of key enzymes in energy production and metabolism, including DNA synthesis.Folic acid functions together with vitamin B12 in maintaining healthy cell division and DNA synthesis. Folic acid is required for healthy red blood cell division. A deficiency of folic acid can cause megaloblastic anaemia resulting in immature, enlarged cells often containing excessive haemoglobin. Folate deficiency is suspected in the initiation of cancer. Folate deficiency in cells and tissues is thought to increase the potential for neoplastic changes in normal cells during the early stages of cancer.Vitamin B12 works with folic acid in many body processes, including DNA synthesis, red blood cell production, and the production of myelin (insulation sheath surrounding nerve cells).
Vitamin B12 like folic acid is a compound that carries and donates methyl groups (a molecule of one carbon and three hydrogen molecules) to other molecules, including cell membrane components and neurotransmitters. Vitamin B12 plays a critical role in proper energy metabolism and nerve function
Look up on Google
Iron - for hemoglobin use
Folic Acid - Structure
Vit. B12 - structure and production

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