Saturday, November 7, 2009

gene therapy. for genetic based problems?

once a chormasone that is the cause of the problem is found
regardless of the problem could be anything i am just interested in dyslexia myself . Does the identification of the chormasone mean that at some point in the not too distant future some sort of gentic treatment could cure the person ?
Also does the treatment if currently used for anything mean the person must be a child or a baby in the womb or could an adult get the same benifits from such a treatment.?
next how far off would you say this all is if it even seems possible now.?
I am interested in the hole thing all the possible things that could be treated but if you know about dyslexia as it relates to this please tell me about that too .
thank you very much .
Answer:
The trouble is that gene therapy doesn't last. Gene therapy is basically removing, correcting and replacing genes, then reinserting the corrected cells into the patient. The effects are temporary until new cells with the same original problem are produced.Gene therapy has been successful at treating some types of disorders such as melanoma where the chromosome mutations are limited to one particular gene (for melanoma, they create super T cells that fight and defeat the cancer). Dislexia would be one of those conditions that involves multiple mutations in multiple genes - an unlucky combination. Science is a long ways from gene therapies on multiple genes and a long ways away from overcoming the temporary nature of gene therapy. It basically works until the inserted cells die off.
If scientists could find the gene responsible for dyslexia, then it would be a candidate for gene therapy treatment. The way gene therapy works is by taking out the old "bad" gene and replacing it with a new gene on the DNA in the chromosome. The way the genetic material is inserted is by something called a vector. One of the most promising vectors for future use is a viral vector. This is because viruses are already programmed to insert genetic information into a cells DNA for its own use. Of course, scientists need to replace the viral DNA with the new beneficial DNA.Gene therapy has been successfully used to treat adult patients. In theory every genetic disorder can be treated. In reality, that task would involve finding every single gene for the genetic disorders and finding a safe, reliable way to insert new genetic material into the patients genome. Also, some diseases, like dyslexia, are thought to only be partially genetically based. It's possible that even if the gene were changed, the patient would still have the disorder due to their environmental influences.

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